Neuropharmacological effects of deltamethrin in rats

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Neuropharmacological effects of deltamethrin in rats

This study examined the effect of deltamethrin on some of the neuropharmacological paradigms in a rat brain such as the motor co-ordination test using a rotarod, the pentobarbitone-induced sleeping time and pentylenetetrazole (PTZ)-induced convulsion as well as the gamma aminobutyric acid (GABA) level. Albino Wistar rats were used as the experimental animals. Different neuropharmacological para...

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Neuropharmacological effects of alfa-cypermethrin in rats

Objective: To study the effect of α−cypermethrin (α−CP) on some neuropharmacological paradigms like motor coordination, pentobarbitone-induced sleeping time and pentylenetetrazole-induced (PTZ) convulsion as well as γ-aminobutyric acid (GABA) level in rat brain. Materials and Methods: Albino Wistar rats were the experimental animals. Different neuropharmacological paradigms like motor coordinat...

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Neuropharmacological effects of standardized aqueous stem bark extract of Parkia biglobossa in Wistar rats

Objective: Parkia biglobossa stem bark decoction is a popular medicinal plant preparation used as calming agent for tensed patients in traditional medicine. The aim of this study was to evaluate the effects of aqueous stem bark extract of Parkia biglobossa (AEPB) and its active fraction AEPBF3 on anxiety, spontaneous alternation behavior, and locomotor activity. The open field apparatus was use...

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Metabolism of deltamethrin in rats.

OBJECTIVE To study the metabolism of 14C-deltamethrin in rats. METHODS Rats were dosed orally and i.p. with a single dose of 14C-deltamethrin (0.64 mg/Kg) body weight. The required dose was applied daily for 3 days. At the end of the experiment, selected organs, such as liver, kidney, fat, intestine, and blood were excised for radioassay of 14C-content. RESULTS Deltamethrin was almost elimi...

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ژورنال

عنوان ژورنال: Journal of Veterinary Science

سال: 2006

ISSN: 1229-845X

DOI: 10.4142/jvs.2006.7.2.133